Sentence examples for upon viability from inspiring English sources

Treatment with ascorbate or Aβ1 40 alone had no effect upon viability (results not shown).

The fact that our detection system is able to identify hsp70 promoter induction at low doses ([ 5]; Figure 2 and Additional file: 1) is an advantage over traditional hepatocyte culture systems which rely upon viability as the key end point.

The current study investigated whether covalent linkage of RGD to the poly ethylene glycol) diacrylate (PEGDA) network could improve upon cell viability and performance of agarose PEGDA IPNs compared to unmodified IPNs (control) and to IPNs with different concentrations of physically entrapped aggrecan, providing a point of comparison to previous work.

Agriculture and tourism, which sustain the Reservation, depend upon the viability of Lake Oahe.

For this reason we tested the effects of the hydrocarbon chain length and polar head group structure of the cationic surfactants upon cell viability.

Incubation with SA/ALA had little effect upon cell viability with 3-hydroxy-4 succin-2-yl -caryolane δ-lactone and a slight decrease in cell viability with 5α-cholestan-3-hydroxy-4 succin-2-yl -caryolane 3-hydroxy-4 succin-2-yl -caryolane

Thus, for example, cannabinoids produce a CB receptor-mediated apoptosis in glioma cells as a result of a sustained production of ceramide [4] and several papers have reported both CB receptor-dependent and -independent effects of cannabinoids upon the viability, mobility and invasivity of both androgen-sensitive and insensitive prostate cancer cell lines [5] [11].

To our knowledge, this possibility has not been investigated in prostate cancer cells, although the effects of [R]-methanandamide, the metabolically stable analogue of anandamide, upon the viability of PC-3 cells are mediated by CB2 rather than TRPV1 receptors [53].

Accordingly, the live cell uptake and impact upon cell viability of 2 towards two human cancer cell lines was investigated.

From the perspective of bioactivity, we observe a comparable cytotoxicity to the anti-cancer drug cisplatin, emphasising how control of the physical properties of this class of complexes can modulate cellular localization and, as a result, impact upon cell viability.

A similar analysis was conducted to estimate the effect of each siRNA upon cell viability in the absence of Olaparib and siRNAs that caused significant cell inhibition alone (Z < −3) were excluded from the final analysis.