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In the tumors we describe, there are more luminal cells than basal cells, and this proportion is robust and constant (upon transplantation).
Notably, tumors that re-formed after X-ray treatment (upon transplantation) were more undifferentiated tumors.
Previous studies have shown that presentation of donor MHC antigens by donor-specific transfusion prior to or upon transplantation promotes transplant tolerance induced by other agents.
She did so, using two newt species with different skin colours, and her experiments confirmed that Spemann's organiser could induce the formation of a second body axis and nervous system upon transplantation – effectively creating conjoined twin tadpoles.
However, ESC-Heps are unable to function as efficiently as hepatoblasts or primary hepatocytes upon transplantation in liver repopulation models.
We investigated whether transgene expression levels influence the immunogenicity of transduced hematopoietic grafts upon transplantation into partially myeloablated mice.
In recent years, appropriate therapeutic cell types and culturing techniques have improved progenitor cell engraftment upon transplantation.
However, cell-based therapies have been limited by the poor survival of grafted cells upon transplantation to the subretinal space.
Upon transplantation onto immune-deficient rats, these pre-formed vascular networks anastomosed to the recipient's vasculature within only four days.
However, evidence has since emerged that ES cells exhibit high rates of immunorejection upon transplantation and form teratomas as a result of their unbridled proliferation [4].
Upon transplantation into mice, these liver buds connected with the host vasculature and formed functional vascular networks similar in density and morphology to those of human adult livers.
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