Sentence examples for upon the potency of from inspiring English sources

As we previously reported a lack of deleterious effects of rAAV gene transfer upon the potency of bone marrow aspirates (Rey-Rico et al. 2015), we did not test a condition lacking vector treatment in this study.

This concentration of J147 converts to approximately 10 mg/kg/day per mouse and was chosen based upon the potency of J147 in our recently published study [ 7].

Preference for binding mode B was proposed based upon the potency of the primary sulphonamide (compound 7, Table 1) in which interaction with the hinge through a bidentate H-bond donor acceptor interaction to Met304 was proposed to place the polar sulphonamide in a more favourable hydrophilic environment.

The rate of plasma HIV decay depends upon the potency of the antiviral regimen [ 49], and as drug exposure in the CNS is almost always lower than at most systemic sites (by virtue of the blood-brain and blood-CSF barriers and other factors reducing drug penetration), we would expect the potency of the regimen in CSF VL to be lower.

Therefore, we split the mesenchymal cell facet into three facets (mesenchymal somatic cell, mesenchymal precursor cell and mesenchymal stem cell) and the monocyte facet into two facets (monocyte and cd14+ monocyte derived endothelial progenitor cell) and assigned sub-facets based upon the potency of the samples.

Amplification of ErbB-2, then, would be predicted to increase the fraction of EGFR in heterodimers upon activation, decrease the degradation of the activated EGFR, and increase the potency of the signal upon ligand binding.

Once we established that the potency of ATAP increases exponentially upon conjugation to MCNPs, we then went on to test the potency of MCNP-ATAP constructs in vivo using a mouse xenograft model.

In order to evaluate the potency of p44/42 signal transduction upon exposure to 17-AAG, the active form of the protein (phosphorylated on threonine and tyrosine residues at positions 202 and 204, respectively) was analyzed.

Our postulate is based on the speculation that the potency of binding will be increased upon cyclo-aromatization reaction due to increased π-stacking interaction.

The potency of glycosaminoglycans in inhibiting complement activation depends upon their extent and positions of polysulfation.

Most DCs have a short lifespan, and upon activation and antigen presentation, they rapidly undergo apoptosis to limit the potency of the immune response that had been elicited.