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On account of G-quadruplex is negatively charged and TMPyP4 positively charged, the tosyl anion was manually docked upon the position of TMPyP4 cation (Figs. 1 and 2).
Potency and efficacy were observed to be dependent upon the position of fluorination, and improvement in pharmacological profile was demonstrated in some cases.
The propensity of the fluorinated ring to be hydroxylated depended upon the position of the fluorine atom, and the oxidation of the methyl group was observed when it was meta to the oxygen.
It was found that the influence of two backbone modifications in the substrate structure was not described additively, i.e. the effect of each structural alteration was dependent upon the position of the second modification.
These two peaks correspond to the fact that depending upon the position of the initial condition with respect to the nullclines of the FitzHugh-Nagumo equations, the points in the phase space follow two different classes of trajectories, as shown in Figure 6.
Whether the compensation for the osmotic pressure gradient predominantly induces HDW or LDW depends upon the position of the equilibrium before application of the gradient.
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Upon assuming the position of CEO of the Economist Group in 1993, she moved to the magazine's London headquarters and branched into businesses such as financial research services and sector analyses.
The placement of novel taxa in the hierarchical taxonomy is based upon locating the position of the taxa in a tree of oral and non-oral reference sequences.
Upon reduction, the position of the bands shifts to 380 383, 425 432, and 505 550 nm and the intensity of the bands drops by 50%.
This finding indicates that, upon deactivation, the position of Cys changes and it can be cross-linked to one of the lysine residues of the 39 kDa subunit in the vicinity.
The stabilities of various defect associates were examined by calculation to investigate their dependence upon the positions of the dopants and vacancies and the relative distances between them.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com