Sentence examples for upon the observation that from inspiring English sources

This is based upon the observation that methylated sites are locally clustered.

Dr. Isobe's study builds upon the observation that pulmonary arterial endothelial cells (PAEC) from PAH patients show disrupted PPARγ-UBR5 interaction, heightened ATMIN expression, and DNA lesions.

In accounting for this unlikely event, however, he fixes upon the observation that "the neighborhood around Cardozo is described as 'a stable enclave with many single-family homes' " and concludes that a stable two-parent family is the cause.

The first description of heartburn dates back to Galen in 200 A.D., who coined the term based upon the observation that diseases of the esophagus often mimicked diseases of the heart.1 Over 1800 years later, Asher Winklestein provided the first clinical definition of acid reflux.

Rather, the Government treats this decision as a 'novel extension' of Fourth Amendment protections, leaning heavily upon the observation that the exclusionary rule has never been extended to 'provide that illegally seized evidence is inadmissible against anyone for any purpose.' Alderman, supra, 394 U.S. at 175, 89 S.Ct. at 967.

The concept is based upon the observation that most gas/liquid synthesis reactions are rather slow compared to the rapid local fluctuations of the gas/liquid hydrodynamics but are sufficiently fast to be considerably affected by the medium- and large-scale mixing behavior in industrial scale bubble columns.

The secretion of NKB by the placenta and the SP-like immunoreactivity released by platelets upon activation (and the observation that synthetic substance P can stimulate aggregation) are 2 such examples.

The 20 kb window was decided upon based on the observation that LTR retrotransposons are generally between 3 and 15 kb of size [ 33], the only exception to our knowledge being the very large Ogre retrotransposons found in legumes [ 34], which have ca. 5 kb LTRs and are therefore ca. 22 kb in size.

Upon siRNA pool deconvolution, the observation that silencing of CCNE1, PLEKHF1, POP4 and TSHZ3 is selectively lethal in cancer cells harbouring their amplification was validated (that is, two or more individual siRNAs were selectively lethal in cancer cells harbouring amplification of the gene silenced; Figure 3A).

For many years, the presence of paused polymerases was proposed to contribute to the rapid rate of transcriptional induction upon heat shock so the observation that depletion of NELF does not affect the rate of heat shock gene induction perhaps came as a surprise 54.

The finding that flies first ran in response to DNp09 activation contrasts with the observation that, upon looming, flies often first paused and then ran, jumped or froze.