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G9a is expressed in myoblasts and its expression declines upon the induction of differentiation.
Surprisingly, 12 out of the 17 genes showed significantly decreased expression levels upon the induction of differentiation (Fig. 7a).
We chose a FUNDC1 LIR peptide10 25 with pS17, which simulates the possible physiological state upon the induction of mitophagy and exhibits a strong binding affinity for LC3B, to co-crystallize with full-length LC3B1 125.
Unlike the RNAs for K8 and K18, K19 RNA levels do not reveal a simple trend upon the induction of neuronal progenitor differentiation (Figure 6D).
We next investigated the sensitivity of hMSCs toward cell death upon the induction of differentiation along the adipogenic or neuronal pathways.
This strain was engineered to express a modified SPB component, Spc110, which can be cleaved upon the induction of a protease.
For the different iPSC types we have identified genes, the expression of which are either lost (L), acquired (A) or retained (R) upon the induction of pluripotency.
Also, it was reported that rapid disruption of the actin cytoskeleton altered the morphology of MSC upon the induction of neuronal differentiation [45].
This revealed that the expression of key senescence-associated genes are down-regulated upon the induction of pluripotency in primary AFCs (AFiPSCs).
These findings raise the interesting possibility that the reduction in Nkx3.1 seen upon the induction of MYC in the mouse prostate prevents the induction of p53 induced apoptosis, thus facilitating MYC's ability to transform these cells.
The nickel-enrichment DNA microarrays identified 33 genes and 37 intergenic regions enriched at least 4-fold in the hha mutant upon the induction of Hha in trans (Table S3).
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CEO of Professional Science Editing for Scientists @ prosciediting.com