Sentence examples for upon the disruption from inspiring English sources

Since further global gene expression changes as well as epigenetic alterations would be anticipated upon the disruption of lamin A functions [75] [76], the organization and modification of naive chromatin might be worth consideration in future studies.

Prevention and control rely upon the disruption of transmission through vector management, environmental modification and modification of human behavior to minimize exposure.

For example, impaired dopaminergic development and altered midbrain morphology is seen upon the disruption of Wnt1 (46) and Lrp6 (47) genes encoding two proteins that function specifically within the canonical Wnt pathway.

Direct experimental investigation of this interaction in human cells and a description of the effects of different carcinogens in different tissues upon the disruption of this signalling are clearly indicated.

This is particularly important, as the cognitive deficits commonly observed after traumatic brain injury, such as executive impairment, are likely to depend upon the disruption of distributed brain networks by diffuse axonal injury.

The gene-gene interaction network reveals intriguing information when interpreted in the context of what we know about the folate pathway and the effect that MTX has upon the disruption of this pathway as it relates to arthritis.

Jill Lepore's characterization of Clayton Christensen's theory of disruptive innovation is, quite reasonably, based on a synthesis of his writing and the work that has built upon it ("The Disruption Machine," June 23rd).

Manfred Kirchheimer Professor, School of Visual Arts New York City Jill Lepore's characterization of Clayton Christensen's theory of disruptive innovation is, quite reasonably, based on a synthesis of his writing and the work that has built upon it ("The Disruption Machine," June 23rd).

Upon homologous recombination the disruption of exon 2 results in a shift of the correct open reading frame in the SWIRM domain of LSD1, prior to the amine oxidase domain that is essential for catalytic activity.

Furthermore, EC hlx1 expression was reduced or lost upon the SU5416-mediated disruptiof of ISV sprouting.

Results of studies, which reported hybrid breakdown upon the enforced disruption of coevolved mito-nuclear genomic combinations, support this contention [ 12, 20– 20].