Sentence examples for upon the copy from inspiring English sources

A number of study end-points were defined, based upon the copy number of HCV RNA in patient sera.

Disease progression, as well as symptom severity, can vary significantly between individual patients with SMA, largely dependent upon the copy number of the near-identical SMN2 gene [ 3, 9].

The gene encoding ToxB displays copy-number variation depending upon the isolate (Lamari et al. 2003), and the severity of the disease produced by these isolates depends upon the copy number (Aboukhaddour et al. 2012; Amaike et al. 2008; Ciuffetti et al. 2010; Strelkov et al. 2002).

Previously, we reported the striking result that treatment of wild-type yeast with low concentrations of inhibitors targeting HP genes can induce the same increased proliferative phenotype as is observed upon reducing the copy number of the HP target, a phenomenon we termed hypertolerance[ 8].

Knockdown of Renilla luciferase expression in HEK 293 cells transfected with the target vector psiCHECK-pTP was significantly increased upon raising the copy number of pTP-mi5 from 1 to 6 (Fig. 8A), revealing the expected positive correlation between amiRNA levels and knockdown capacities.

Upon stepwise transformation, the copy numbers of crtYB was continuously increased leading to an almost saturated level of phytoene synthase as indicated by total carotenoid content.

The Ct value that is dependent upon the starting copy number of the target is defined as the cycle number at which a statistically significant increase of the reporter fluorescence can first be detected.

In spa/spa TG456 mice, one of three strains generated with this construct, which expressed very low levels of GlyR β transgene-dependent mRNA and protein, the spastic phenotype was found to depend upon the transgene copy number.

Note significant relative changes in the copy number of Dlic and Dmn upon increasing or decreasing copy number of SL1.

Upon duplication the gene copies might diversify, thus developing new functionalities (neo- or subfunctionalization), they might contribute to genetic robustness or one of the copies might be lost (for review see [ 61]).

The cafe, opened three years ago by Jenifer Constantine and Trippy Thompson, a couple of other Williamsburg expatriates, is a place where one might stumble upon a copy of The Brooklyn Rail, the Greenpoint-based publication covering the local arts scene.