Importantly, inhibition of notch1 signaling with γ-secretase upon MI impairs the commitment of heart resident CPCs into the myocytic lineage [ 39].
This approach allows risk assessment analysis, based upon formulation complexity, to be conducted prior to the commitment of resources and candidate selection for clinical development.
" Controlling measles requires the commitment of all.
Retirement security also depends upon keeping the commitments of Social Security, and we will.
The meeting in Paris is also expected to include an action-agenda with more commitments from companies, countries, cities, financial institutions, and other key actors that build upon the commitments coming out of Climate Summit this past September.
While the senior physicist rejects Milne's operationalism and attacks upon the geometrical commitments of relativistic proponents, he is considerably more forgiving about Milne's hypothetico-deductivism, and even goes so far as to remark Milne's "brilliant record in astrophysical discovery".
He said the university's reputation for excellence had been "built upon the expertise and commitment of the staff over many years".
The White House did this by rescinding or, more accurately, indicating its desire to rescind the two sets of Obama-era regulations upon which the commitment was based: a set of stricter auto-efficiency standards and a series of rules governing emissions from power plants.
For example, in Ecuador the risk governance infrastructure relies upon the engagement and commitment of local representatives (e.g. chiefs and elders) and volunteers, such as hazard wardens/monitors, for both hazard data gathering and risk mitigation.
ZEB1 mRNA levels did not change upon commitment of the cells to the adipocyte lineage (Day -3), but it did increase at confluency (Day 0), decrease with the initiation of differentiation (Day 1), and then increase with lipid accumulation (Day 4).
