Sentence examples for upon targeted from inspiring English sources

An empirical method is described for developing and optimizing immunoassays on the CombiMatrix ElectraSense® microarray based upon targeted deposition of polypyrrole (Ppy) and capture Ab.

10.7554/eLife.08474.006 Figure 2. Decreased ULBP1 expression upon targeted mutation of screen hits.

Identical phenotypes, namely an arrest of mammary gland development before outgrowth of the primary sprout, occur upon targeted deletion of PTHrP or the receptor PTHR1 [ 14].

Drug-based strategies for chemoprevention of the future may predominantly rely upon targeted therapies with tolerable but defined toxicities for treatment of individuals diagnosed with intraepithelial neoplasias.

The increased plant size obtained upon targeted downregulation of a specific GAUT12 homolog as reported here suggests that a controlled manipulation of this gene to yield greater plant growth could be used to improve feedstock for the biofuel industry.

Importantly, our conclusion that the N-terminal region is required for DNA-binding is confirmed by the abolition of DNA-binding upon targeted mutation of SYCP3 N-terminal region, demonstrated through EMSA and FP. 3) If possible, it would be good to verify the oligomerisation state of the studied mutations by SEC-MALS or other methods, as was presented for SYCP3 FL and SYCP3 core constructs.

Interestingly, clear differences were observed upon targeting distinct epitopes of the same receptor.

Upon targeting using transferrin ligands, the nanoparticles showed enhanced cellular uptake and synergistic cytotoxicity in ~ 92% of cells, particularly in iron-deficient microenvironment.

Upon targeting, Cas9 generates DNA double-strand breaks (DSBs) and facilitates the repair or insertion of mutations, insertion of recombinase recognition sites, or large DNA elements.

Here, we report that TLQP-21 is intrinsically disordered and undergoes a disorder-to-order transition, adopting an α-helical conformation upon targeting cells expressing the C3aR1.

Upon targeting on the cell surface, the MHC I/peptide complex can activate CD8+ T cells through interaction with the corresponding T cell receptor [24].