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At one level, 'breakdown' is one of those words that operates as shorthand; many of us routinely refer to being on the verge of a breakdown when we want to convey just how put upon, stressed and pressurised we are, without really meaning it at all.
Upon stressed conditions, UBB+1-triggered cytotoxicity was markedly increased in Δ yuh1 as compared to wild-type cells upon comparable fl-UBB+1 steady-state levels.
In contrast, UBB+1-mediated cytotoxicity was significantly decreased in strains depleted from isoform 2 of cytochrome c (Δ cyc7) upon stressed conditions.
UBB+1-triggered cytotoxicity was significantly relieved in Δ ubr2 cells upon stressed conditions, in which Rpn4 is stabilized and consequently the UPS activity is increased (Kruegel et al., 2011).
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In turn, these changes determine the specificity, timing, and concentration of gene products expressed upon stresses [14].
However, upon stressing the cells using CCCP or hydrogen peroxide, Park formed a complex with Clu (Fig. 6B).
It cannot be stressed upon enough, but be yourself.
Upon stress signaling, cytosolic p66Shc translocates to mitochondria to directly stimulate hydrogen peroxide generation.
The actual fold change values upon stress treatment are given in the right column.
The alloy showed high stability upon stress-free thermal cycling, variation in transformation temperatures being ±1 °C.
The resistance increases upon fiber breakage and decreases upon stress-relaxation-related fiber rearrangement.
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