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Upon stress signaling, cytosolic p66Shc translocates to mitochondria to directly stimulate hydrogen peroxide generation.
The actual fold change values upon stress treatment are given in the right column.
Adopting a protected state upon stress exposure reduces the time-averaged growth rate, see Fig. 4A.
In contrast, Pol II-mediated TR experiences only a transient increase immediately upon stress.
LTRs do have promoter functions and are activated upon stress [37].
Moreover, protein-carbohydrate interactions decrease upon stress, while protein-protein and carbohydrate-carbohydrate interactions increase.
HSF is present in cells at all times and is activated to its transcriptionally competent form upon stress.
Both TR and RA for this gene increase upon stress, as determined in the GRO experiments (Fig. 2).
Our results show that rapidly adopting a downregulated state upon stress exposure may reduce the long term fitness.
It has been considered that ABA is a "stress hormone," because its levels increase upon stress treatment.
Upon stress stimulation, the Sho1 branch triggers the activation of a distinct MAPKKK Ste11, which then activates Pbs2.
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