Sentence examples for upon linkage from inspiring English sources

Thus, it is necessary to investigate the impacts of selection upon linkage analyses in order to obtain unbiased estimates of QTL position and effect.

Based upon linkage disequilibrium with 2DL5B or 2DL5A, it has also been suggested that 2DS3 and 2DS5 can similarly be present in either centromeric or telomeric locations [31], [40], [41].

We analyzed 30 SNPs spanning a 237 kb region around ISL1 on chromosome 5q11.1, selected to capture variation in this region based upon linkage disequilibrium patterns in subjects of European ancestry (http://www.hapmap.org).hapmap.org

In all cohorts, follow-up was based upon linkage to mortality registries.

%FGV data were obtained from the SFMR through a cooperative agreement upon linkage to MWS data for all consenting women.

In addition, this study was retrospective, relying upon linkage with routinely collected administrative data, and some false-positive and false-negative linkages do occur.

Our results show that such tools, intended to improve upon complete linkage, actually perform significantly worse.

Based upon the linkage disequilibrium (LD) structure of the region, 33 genes near APOE (chromosome 19: 49.6–50.6 Mb) were removed from the analysis.

These results suggest that the activation of the tumor invasiveness is dependent upon HA linkage to CD44st.

This is probably because CS GAG chains are synthesized differently depending upon the linkage position on the core protein, aggrecan.

Both approaches map functional polymorphisms based upon their linkage with known polymorphic markers and benefit from knowledge of the population structure for an effective experimental design.