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The fact that VFA did not accumulate in time suggests a stable anaerobic degradation process following the addition of the H2 producers therefore the system operated in a balanced fashion upon intensification.
An earlier improvement occurred with immediate combination arms, but after initial MTX monotherapy in those patients who lacked sufficient response a rapid improvement to similar levels as with immediate triple therapy was seen upon intensification of treatment.
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The further implementation of new bioprocesses, using biocatalysts in various formats, for the synthesis of chemicals is highly dependent upon effective process intensification.
Upon Rick's intensification to a Category 4 hurricane, officials in Mexico raised the alert level in Guerrero, Jalisco and Michoacán to severe.
However, we are aware of only one prior study that examines effect of MHC upon clinicians' decisions about intensification of antiglycemic medications following an elevated Hemoglobin A1c (HbA1c) value [ 15].
In this work, we harness the previously presented computational technique, flux-sum analysis [ 22], to identify metabolite targets that will "force" the overproduction of desirable by-products or the reduction in formation of undesirable metabolites upon the attenuation or intensification of metabolite turnover, also known as "flux-sum".
We excluded institutionalized patients (the focus was upon outpatient diabetes management) and patients with serious conditions likely to alter goals of care (the focus was upon patients eligible for routine intensification).
Major clinical trials have now investigated the impact of intensification of glycemic control upon CV outcomes, as well as the CV effects of glucose management with newer antihyperglycemic agents.
Intensification was rather rapid upon the storm's reformation – the depression reached tropical storm status on August 20 and then typhoon intensity two days later.
Furthermore, the chapter presents an example of a "Process Intensification Methodology," a case based upon intensified chemical reactor in Britest and BHR Group procedures.
Upon becoming a tropical cyclone, only slight intensification was anticipated.
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