Sentence examples for upon fc from inspiring English sources

Immune thrombocytopenia depends upon Fc receptor-mediated phagocytosis that involves signaling through the SH2 tyrosine kinase, Syk.

The increased efficacy of native Mabs 9 and 10 appeared dependent upon Fc receptors on mononuclear cells.

Moreover, cultured Btk-deficient mast cells revealed defects in degranulation and cytokine production upon Fc εR stimulation [ 14].

We demonstrate that c-Fms activation primes macrophage TNF production such that macrophages produce much greater amounts of TNF upon Fc receptor stimulation, an important trigger of synovitis in RA [ 34].

Upon FC-FCM contact and adhesion, the plasma membranes breakdown leading to cytoplasmic continuity [4].

The response is also influenced by the inhibitory FcγRIIb, where the immune receptor tyrosine-based inhibitory motif (ITIM) becomes phosphorylated upon Fc-ligation, thereby inhibiting ITAM- signalling [20].

"Nor did the non-disclosure have the effect that any of the registered players were ineligible to play, and for this and other reasons no sporting sanction or penalty should be imposed upon Rangers FC".

Additionally, it has been suggested that sialylated IgG in vivo switch from its anti-inflammatory activity with subsequent reduced antibody effector activity, to a pro-inflammatory/toxic activity upon decreased Fc sialylation [13].

Upon binding Fc, C1q undergoes a conformational change, activating the associated C1r/C1s proteases.

Further, we determined the effects of imatinib and GW2580 on the ability of macrophage colony-stimulating factor (M-CSF; the ligand for c-Fms) to prime bone marrow-derived macrophages to produce tumor necrosis factor (TNF) upon subsequent Fc receptor ligation.

In order to get more insights into the magnetic behavior of IOMNPs, the thermal dependence of the magnetization upon field cooling (FC) and zero field cooling (ZFC) has been recorded for all samples in a 50 Oe external field between 2 and 300 K.