upon engagement with

USAGE SUMMARY

The phrase "upon engagement with" is correct and usable in written English.
It can be used to indicate the moment or condition when someone interacts or becomes involved with something or someone. Example: "Upon engagement with the new software, users will notice a significant improvement in efficiency."

✓ Grammatically correct

Science

News & Media

Academia

Human-verified examples from authoritative sources

Exact Expressions

12 human-written examples

Sundaramoorthy, R. et al. Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes.

Nature

Upon engagement with the EphB4-expressing placode cells, ephrinB2-expressing CNC cells suppress the chemotactic response and undergo an Eph/ephrin repulsion that is independent of TBC1d24.

Nature

This is consistent with ephrinB2 within the CNC inhibiting the activity of the SDF-1 receptor (C-X-C chemokine motif receptor 4 (CXCR4)) upon engagement with the cognate EphB receptor, as has been shown for cerebellar granule cell movement61.

Nature

In addition to the generation of a pulling force, the YidC machinery itself, which has a unique helix-turn helix structure protruding into the cytoplasm, may sterically disrupt the nascent chain-ribosome surface interaction upon engagement with the MifM nascent chain, thereby contributing to the arrest-releasing event.

Nature

Notch1 activation in maturing thymocytes occurs upon engagement with its ligand, expressed on the thymic stromal cells [ 14, 15].

BioMed Research International

CD40L is expressed on T cells and contributes to disease pathogenesis by stimulating antibody production upon engagement with CD40 expressed on B cells [ 98].

CKJ: Clinical Kidney Journal

Human-verified similar examples from authoritative sources

Similar Expressions

48 human-written examples

These data indicated that while the mentors did reflect upon their engagement with the youth, they were unable to clearly articulate specific areas of focus of that metacognitive process.

International Journal of STEM Education

This assembly is due to the clustering of integrins upon their engagement with ECM components and to the subsequent recruitment of scaffolding and signaling proteins [8].

Plosone

Upon its engagement with the ligands PDL1 (B7H1) or PDL2 (B7DC), it provides negative signal to the T cells [ 81].

BioMed Research International

Upon the engagement with nAChR in non-neuronal cells, nicotine activates calmodulin-dependent protein kinase II, PKC, phosphodylinositol-3-kinase (PI3K /Akt and Rac family that are often involved in the regulation of cell growth, adhesion or migration [ 7, 18- 20].

Breast Cancer Research

FcγRIIB is able to suppress or block B cell receptor activation by transmitting inhibitory signals via its cytoplasmic immunoreceptor tyrosine-based inhibitory (ITIM) motif upon simultaneous engagement with the B cell receptor [ 3].

Arthritis Research and Therapy

Expert writing Tips

Best practice

When using "upon engagement with", ensure that the sentence clearly indicates what action or change occurs as a result of the engagement. This makes the relationship between the engagement and its consequences explicit.

Common error

Avoid using "upon engagement with" in very informal contexts. The phrase is somewhat formal and may sound out of place in casual conversation or informal writing. Opt for simpler alternatives like "when interacting with" or "as soon as you start using" for a more natural tone.

Linguistic Context

The phrase "upon engagement with" functions as a prepositional phrase introducing a condition or trigger for a subsequent action or event. It specifies when something occurs, indicating immediacy and direct consequence. Ludwig AI confirms this usage is grammatically correct and suitable for describing an action that immediately follows an interaction.

Expression frequency: Uncommon

Frequent in

Science

60%

News & Media

20%

Academia

10%

Less common in

Formal & Business

7%

Encyclopedias

2%

Wiki

1%

Ludwig's WRAP-UP

In summary, "upon engagement with" is a prepositional phrase used to indicate that an action or event occurs immediately after an interaction begins. Ludwig AI confirms that the phrase is grammatically correct and suited for formal contexts. While "upon engagement with" is relatively uncommon, it is frequently found in scientific and academic writing. When employing this phrase, ensure that the subsequent clause clearly outlines the direct consequences of the interaction. Consider using alternative phrases like "when interacting with" in less formal settings to maintain a natural tone.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

when interacting with

Focuses on the act of interaction at a specific moment.

when involved with

Emphasizes the state of being involved as the trigger.

on interacting with

Similar to "when interacting with" but slightly more formal.

on involvement with

Highlights the commencement of involvement.

as soon as one engages with

Highlights immediate action when the interaction starts.

at the start of interacting with

Focuses specifically on the initial phase of interaction.

at the commencement of interaction with

More formal and emphasizes the beginning of the interaction.

once in contact with

Highlights the moment of contact as the trigger.

when connected to

Highlights the connection that happens at the moment of engagement.

when faced with

Highlights the challenge that emerges at the moment of engagement.

FAQs

How can I use "upon engagement with" in a sentence?

Use "upon engagement with" to describe an event that immediately follows an interaction or involvement. For example, "Upon engagement with the antigen, the immune cells activate."

What are some alternatives to "upon engagement with"?

You can use alternatives like "when interacting with", "as soon as one engages with", or "on interacting with" depending on the context.

Is "upon engagement with" formal or informal?

"Upon engagement with" is considered a formal phrase and is best suited for academic, scientific, or professional writing. In more casual contexts, simpler alternatives might be more appropriate.

What's the difference between "upon engagement with" and "during engagement with"?

"Upon engagement with" implies that something happens immediately at the start of the interaction. "During engagement with" suggests that something occurs at some point while the interaction is ongoing.