Sentence examples for upon dysfunction of from inspiring English sources

Conversely, complex II-dependent respiratory capacity is significantly impaired upon dysfunction of membrane-bound subcomplex 1β subunits.

The cause of death is not known and could only be speculated upon as dysfunction of the placenta, hormonal changes or a nonvisible defect in the calf, or some combination of these.

Secondly, the effect of carnitine supplementation upon the cardiac dysfunction of diabetes in these animals was evaluated.

But, the explosion of the Tea Party upon the scene, the dysfunction of the 112th Congress, the highly charged and negative tone of most of the presidential contest of 2012, and a Pew Research survey that shows the partisan "values" gap between us as citizens at an all time high provide ample evidence that we have grown more divided rather than more united as a nation over the past six years.

Importance of an individual miRNA is reflected in the diseases that may arise upon the loss, mutation or dysfunction of specific miRNAs [21] [23].

The hallmark of this condition is the reversibility of ventricular dysfunction upon restoration of coronary blood flow reperfusion.

In spite of this genetic heterogeneity, leukocytes from WHIM patients share in common dysfunctions of the CXCR4-mediated signaling pathway upon exposure to CXCL12.

In order to examine whether the increased susceptibility to oxidative stress is due to elevated basal levels of ROS upon COX dysfunction, we analyzed the amounts of mitochondrial superoxide in KCN-treated HeLa, 143BΔCOX and COX10−/− cell lines (Supplementary Figure 2A).

Our findings agree well with the hypothesis that relative impairment of bipolar attachment and successful segregation upon condensin dysfunction (i.e. decondensation of centromeric chromatin) is a function of the number of microtubule attachment sites (Fig. 8A) and size of kinetochores in different organisms.

For the first time in any animal model of neurodegeneration, we have demonstrated progressively increased risk of acute cognitive dysfunction upon application of a standardized systemic inflammatory insult in animals with advancing synaptic and white matter pathology.

A number of observations suggest that cellular dysfunction upon loss of U34 modifications may be tied to inefficient translation via a subset of tRNAs with modified U34.