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The present study was thus designed to explore the mechanism of how ebselen triggers apoptosis upon depletion of intracellular thiols.
Keshishian et al. reported a 1000-fold improfement of limit of detection (LOD) upon depletion of seven high abundant plasma proteins by strong cation exchange chromatography [123].
The system was first validated by FRAP analysis of GFP-Dad1 upon depletion of Climp63 (Fig. 6A); as previously reported, the mobility of translocon was increased (Fig. 6B).
In addition, we find that nucleosome occupancy is reduced at specific loci in favor of subnucleosomes upon depletion of esBAF, including sites of histone H2A.Z localization.
Upon depletion of this energy, the production ceases or the oil production rate becomes so small that it will not be economical to operate.
We next examined mitotic progression upon depletion of hCdc14B in synchronized HeLa Kyoto cells (Fig. 3A).
Less severe effects on ribosomal subunit balance were observed upon depletion of rpL1 and rpL40.
Upon depletion of PKD2, we observed an altered morphology and a reduced number of myotubes (Figure 5B).
Interestingly, an aberrant outgrowth of PC in cycling cells was recently described upon depletion of Cep97 and CP110 proteins [47].
We also showed, for the first time, that puncta-like co-localization of YFP-STIM1 and ORAI1 appeared upon depletion of Ca2+ stores in cultured rat neurons [21].
Upon depletion of the glycerol the continuous culture was initiated with a 0.652 M methanol-containing medium at a dilution rate of 0.04 h−1.
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