This hypothesis is based upon previous demonstration that stronger virus-induced MAPK activation resulted in higher viral replication efficiency [50].
24 These findings built upon their previous demonstration that reduced levels of miR-150 levels were associated with increased LV remodelling after ST segment elevation myocardial infarction (STEMI),w34 and herald promise in the use of miRNAs, or panels of miRNAs, as diagnostic and prognostic predictors of heart failure.
Upon the demonstration that ME can activate insulin-induced ERK pathway, we investigated whether ME is also able to promote GLUT4 translocation.
Moreover, leukemia cells have been associated with angiogenesis, upon the demonstration that leukemia progression is accompanied by an increase in bone marrow vascularization [ 14].
The field was significantly advanced upon the demonstration that synthetic duplexes of 21 nucleotide RNAs could mediate gene specific RNAi in mammalian cells, without invoking generic antiviral defense mechanisms [ 2, 3].
These results provided the first demonstration that regulated secretory proteins and constitutive secretory proteins were sorted into two distinct vesicle populations directly upon exit from the TGN, in support of the "sorting for entry" hypothesis.
It was driven, instead, by "centrist", self-righteously nonpartisan pundits who seized upon Ryan as their demonstration that see, there are honest, reasonable conservatives who must be taken seriously.
This is consistent with our demonstration that LAZ1 mRNA accumulates in acd11/nahG upon BTH treatment, as well as developmentally in senescent tissue [29].
Nevertheless, at least some forward causal effect of obesity upon CO2 emissions is suggested by our novel empirical demonstration that obese and perhaps overweight individuals had larger cars (an association which we judge unlikely to reflect reverse causality).
In recent decades, plant defences have grown into a vast field of investigation following the demonstration that many of these traits are only activated upon attack [6].
