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The glutaminase activity has been shown to increase upon complex formation, yet the mechanism of this activation is unknown (15).
The four-stranded, antiparallel, β-pleated sheet formed a lid covering the binding pocket, indicative of the formation of a "closed" conformation of STING upon complex formation.
In both cases (LAOBP and GBP), the changes upon complex formation are consistent with intuition.
As described above, the H-bond network is significantly altered upon complex formation.
These shifts could be concerned with changes in molecular symmetry and electronic structure upon complex formation (Abeer et al. 2013).
McKinsey defines knowledge-work automation as "the use of computers to perform tasks that rely upon complex analysis, subtle judgments, and creative problem solving".
Pandora is an app based upon complex algorithms that uses the concepts of the " human genome" to know what music to play.
LISA's performance is stable for subsets defined by functional composition and extent of conformational changes upon complex formation.
The greatest correlation is found between the binding free energy and apolar surface burial upon complex formation.
This research project focuses upon complex batch processes with high quality demands which are hard to meet.
The performance of such pavements depends upon complex environmental factors including shrinkage and swelling of the subgrade.
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CEO of Professional Science Editing for Scientists @ prosciediting.com