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Transduction occurs upon binding of an analyte with a transducer.
The allosteric response of a β-galactosidase molecular sensor containing a B-cell epitope from HIV has been finely dissected upon binding of an effector monoclonal antibody, within a wide range of standard concentrations of both enzyme and substrate.
Upon binding of an AlexaFluor555-labeled SSB, both DNA extension change, Δ x, and single-molecule FRET are measured simultaneously.
Upon binding of an agonist, the receptor changes its conformation, and acts as a guanine nucleotide exchange factor (GEF).
The rRNA transcription is also regulated by nucleolar-remodeling complex, which promotes gene silencing upon binding of an intergenic promoter rRNA of about 100 200 nucleotides in mouse fibroblast cells.
Upon binding of an extracellular ligand to the respective receptor latent signal transducers and activators of transcription (STATs) are activated by Janus kinases (JAK) leading to rapid nucleocytoplasmic cycling of STATs.
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Upon binding of a SERM to ER, the transcription factor is still allowed to bind to DNA but the initiation of transcription is inhibited due to an insufficient conformation change of the receptor.
These regions become structured upon binding of a ligand.
Significant conformational changes in the cytoplasmic and transmembrane regions were observed upon binding of a nonhydrolyzable ATP analog and accompanied by altered hydrogen/deuterium exchange in the Walker A motif of one of the nucleotide-binding domains.
In order to better understand the structural basis of ubiquitin UIM recognition, we have characterized changes in the structure and dynamics of ubiquitin upon binding of a UIM domain from the yeast Vps27 protein.
These high-amplitude motions of the flexible loops are found to be weakened significantly in the presence of the substrate or a weak inhibitor (NOG), and damped out upon binding of a potent and selective inhibitor (NODP) in the active site.
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upon acceptance of an
upon introduction of an
upon delivery of an
upon evidence of an
upon reception of an
upon acquisition of an
upon exercise of an
upon expression of an
upon part of an
upon synthesis of an
upon insertion of an
upon conviction of an
upon incorporation of an
upon application of an
upon receipt of an
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