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This might be explained by the reason that we detected SIRT6 levels upon a transient stimuli, since cells were replaced with fresh medium and cultured for different time after exposure to H2O2.
Concerning the distribution pattern of the neurite lengths, the population of long-neurite-bearing cells was much smaller than the population under optimal conditions, whereas the population of short-neurite-bearing cells decreased upon a transient (1 h) second stimulation, indicating that sustained stimulation was required for the prolonged extension of the neurites (see Figure S2D,G,I).
In cell signaling terminology, adaptation refers to a system's capability of returning to its equilibrium upon a transient response.
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Patterning along the midline body axis in vertebrates depends upon signals from a transient embryonic tissue, the notochord [1], [2], [3].
Furthermore, mitochondrial biogenesis is mediated by the activation of CREB upon stress and a transient decrease of ATP levels probably caused by an increased energy demand [35].
Indeed, upon cisplatin treatment, a transient knockdown of BRMS1 restored the diminished protein levels of p300 and CBP in iASPP-depleted cells.
Upon influenza vaccination a transient rise in circulating ASCs is mainly reflective of vaccine-induced cells and up to 80% of such cells secrete antibodies specific to the antigens in the vaccine.
Consequently, the average strength of junctions decreases (after a transient) upon an increase of the strain rate, which leads to negative SRS.
As a consequence of diminished food intake, C57B6/j mice attenuated their growth rate upon HP diet, exhibiting a transient decrease in body weight followed by a phase of stabilization (Fig. 1B).
Diagnostic and assessment criteria are founded upon the notion of a transient episode with a rapid return to a 'normal state'.
An early signal generated by the activation of EGFR upon ligand binding is a transient increase in the cytosolic concentration of free calcium ion ([Ca2+]cyt) [ 44].
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