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Even if a single challenger emerges, they face an uphill challenge in September's members' vote, with a YouGov poll for the Times saying that Corbyn would defeat both Smith and Eagle by more than 20 percentage points.
Cameron's uphill challenge becomes even steeper.
"It was an extreme challenge, an uphill challenge".
"It's a real uphill challenge to battle the white-guyness," Mr. Gibbons said of himself.
Mr. Gingrich conceded that the race had often been an uphill challenge.
"History shows," said Karl Rove, Mr. Bush's chief political adviser, "that it's an uphill challenge".
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But even with all the uphill challenges, there are successes, even if not perfect ones.
Additionally, it faces uphill challenges – a slowing growth curve and unclear product pipeline.
Amy faces uphill challenges, but is also getting important help—and Medicaid is a key piece of the family's puzzle.
In addition to Ose's race against Bera, Republican strategists hope anger over water restrictions could help them with otherwise uphill challenges to Democratic incumbents Jerry McNerney of Stockton and Jim Costa of Fresno.
And pushing a 30-pound bike uphill is a challenge to many.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com