Sentence examples for upfront phase from inspiring English sources

More recently, a prespecified interim analysis of the results from an upfront phase III clinical trial in newly diagnosed glioblastoma patients, comparing NovoTTF-100A plus adjuvant temozolomide vs adjuvant temozolomide alone, revealed significantly improved patient outcome with a respective progression-free survival of 7.1 vs 4.0 months and OS of 19.6 vs 16.6 months (Stupp et al, 2014).

"Obviously, this upfront investment in future phase infrastructure speaks to our confidence in the future of Ballpark Village and the downtown in general," said Mr. Martin, who is overseeing the project.

Careful, detailed, upfront planning, encompassing all phases of facility programming, planning, design, construction, and commissioning is required to ensure that the facility functions to effectively support the institution's research goals.

Our findings of biological activity of the TMZ/BV regimen in the upfront setting provide support for phase III randomized controlled trials investigating the use of this and other therapy combinations.

Although the strongest rationale for the use of the trimodality therapy stems from the promising results of clinical phase II data, upfront systemic chemotherapy offers several practical as well as theoretical advantages (Pisters et al, 2000).

The topics covered here can change the mindset to better design security and consider GRC upfront in the project-planning phases to detailed implementation considerations for security planning on SAP application services and databases.

For these reasons, the European Organisation for Research and Treatment of Cancer 30073 randomised phase III study, comparing upfront sunitinib followed by nephrectomy against nephrectomy followed sunitinib will open in 2010.

We conducted a phase II trial of upfront 5-day temozolomide (TMZ) and bevacizumab (BV) in patients with newly diagnosed unresectable or multifocal glioblastoma.

Others say the project could be done in phases to moderate the upfront costs.

We designed a phase II study evaluating the upfront combination of clofarabine and daunorubicin in acute myeloid leukemia (AML) patients ≥ 60 years old.

In this manuscript, two single-arm phase II prospective studies, evaluating upfront sunitinib before nephrectomy, are assessed together and individually to address these issues.