Although this is not an argument for such a model, it adds further evidence that upfront investment in basic infrastructure can be financially supported by a resulting reduction in illness.
That the company, NCM Media Networks, part of National CineMedia, would want to make an upfront presentation is the latest evidence that the 2012-13 upfront week is shaping up as possibly the most crowded ever.
However, presenting evidence of effectiveness upfront, alongside providing examples where HPFI schemes have been used to good effect, may have helped reassure participants about their effectiveness and limit the focus they had on this issue.
It is important to state upfront that I have no information or evidence to know whether the person they describe committed espionage or not.
Together with the extensive additional data and edits provided in our revised manuscript, we provide multiple lines of evidence that SOX2 induction contributes to upfront and acquired resistance to erlotinib in EGFR-mutant lung cancer cells.
Until the results of this trial and the FACE trial are reported, however, clinicians need to rely on the available clinical evidence, which strongly favors the use of upfront letrozole for PMW with HR+ early breast cancer.
But when I spoke to OFFA it told me there was no evidence that students were influenced by the scale of upfront bursaries when choosing universities.
This is the first time an upfront adjuvant trial has demonstrated improvement in OS, and it provides further evidence that preventing early DM translates into a long-term survival advantage.
He cited continuing strong ad sales in the quarter — up 40 percent — as evidence that CBS should gain "solid double-digit increases" in its upfront sales.
Accordingly, combined HD-MTX/HD-AraC should be seen as the new standard upfront treatment in PCNSL, as it is supported by the best level of evidence available in this disease (Ferreri et al, 2009).
