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Subsequently, we planned to synthesize 7-arylbenzofuran derivatives which are present in a number of natural products.[ 19] Note that the synthesis of 7-arylbenzofuran from simple precursors remained problematic up to date (Scheme 3).
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The instability of anomuran taxonomy in recent years highlights the need for continued phylogenetic study of this group at many levels, and we for now elect to follow the most recent and up-to-date classification scheme [ 17, 18, 22, 44- 46].
Especially, we evaluated the feature selection here together with the classification using an up-to-date double CV scheme to reduce potential bias.
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