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These aligners take advantage of the short read lengths for speeding up the alignment (by using hash tables for speeding up seed identification) which allows the processing of a larger number of reads in a reasonable time frame: Eland (Illumina): the mapping algorithm which is provided by Illumina as part of its analysis pipeline, divides each read into four parts (A, B, C and D).
We exploit this property to speed up the alignment process (Figure 6).
MegaBLAST was developed to speed up the alignment for query sequences that are highly similar to the reference sequences and was used to align large-scale sequencing data.
Therefore, to speed up the alignment process we used NUCMER pipeline of MUMMER [ 34].
In addition, one may want to use automatically produced local alignments as anchor points to speed up the alignment procedure as outlined in [ 18].
However, as the number of substitution errors appears much more than the insertion/deletion errors, IDBA-Tran considers substitution error only for speeding up the alignment process.
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It's not that hard, just don't mess up the alignments and colors.
It depends, it seems, who turns up on the day, which side of the bed they wake up on, the alignment of the moon.
MULTAL deploys a sequential branching method to align the two closest sequences before building up the final alignment by subsequently aligning the next closest sequence to it.
Virtually any non-homogeneous model can thus be set up, provided the alignment is not a mix of nucleotide, amino-acid or codon sequences.
After cleaning up the nucleotide alignments for poorly aligned regions, the 1,486 multiple alignments were concatenated in a single alignment of 431,655 codons.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com