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For teams with many unknowns, the unpredictability of the off-season schedule is yet another unwanted variable to contend with.
This could introduce an unwanted variable, complicating data interpretation.
Genetic background is known to affect the phenotypic expression of a gene mutation, thus a mixed background introduces an unwanted variable for the phenotypic and molecular characterization of tumors (32, 33).
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Control of unwanted variables is paramount for research animal facilities because the data obtained from research animals can otherwise be affected, confounding interpretation of research results.
Although this system of measuring can introduce unwanted variables (see research limitations), it is accepted as a consistent mechanism of recording data due to the inter-rater reliability testing conducted by the researcher.
Genome complexity reduction techniques are, however, tedious and can introduce unwanted variables into genotyping assays.
Surrogate variable (SV) analysis using the R package sva [ 43] was performed to account for unwanted variability in the linear modeling.
All (d_{3j}^)'s are the unwanted deviation variables for the goal (i.e., (begin{array}{*{20}c} {M - d_{j} ge 0} & {j = 1,2, ldots,n} end{array})) that make M the maximum deviation, and the whole (d_{3j}^)'s are the wanted deviation variables for the same goal (i.e., (begin{array}{*{20}c} {M - d_{j} ge 0} & {j = 1,2, ldots,n} end{array})) in which all d j deviation variables are unwanted as well.
To identify meaningful classes of genes regulated exclusively by HU, we developed an unsupervised data-clustering method able to avoid numerous single-gene hypotheses by partitioning the transcriptome profiling data into an optimal and biologically relevant number of clusters and by removing the interference of the unwanted growth phase variable.
To remove any unwanted seasonal variability in each of our models, we also included a variable to represent each month during the study from February through June.
Unwanted variation due to variable raw material quality is often a problem in production processes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com