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It also argues that the Treasury's work would be disrupted by "misinterpretation of the 23 million lines of raw and unvalidated data" and by "a high volume of follow-up requests and enquiries".
They argued [1.64Mb PDF] that potential misinterpretation of 23 million lines of raw and unvalidated data and a high volume of follow-up enquiries would be too disruptive to the Treasury's work.
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Our model results are unvalidated by in vivo data and should be treated as estimates only.
However, in vitro validation studies are necessarily based on data generated by these unvalidated methods.
A subsequent small study in stage IV melanoma patients reported that lower vitamin D levels were associated with poorer survival, but in the absence of further published data the Leeds study remains unvalidated.
Thirty-seven markers, typically unvalidated or rare non-synonymous polymorphisms or unvalidated putative polymorphic miRNA binding sites, were monomorphic, making the total number of statistically analyzed SNPs 144 (92 in stage I, and 52 in stage II; Table 2).
Both data sets are provided "as is", i.e., essentially unvalidated: GOME-2 BrO is a fairly recent product from retrievals that have been mirrored on the original GOME-1 approach, and OMI data are provided in a new version (v1.9) that has yet to be validated against correlative measurements.
The study also used unvalidated or disputed surrogate endpoints, made claims not supported by trial data, and downplayed adverse effects.
The unvalidated cotton test assesses improvement in ENS-related symptoms.
Despite the number of studies undertaken to address TRIPP Stages 1 and 2 (injury surveillance, aetiology and mechanism of injury), most triathlon studies have been limited by retrospective designs with substantial, and unvalidated, recall periods, inconsistency in the definitions used for a reportable injury and exposure to injury, or a failure to capture exposure data at all.
Without this experimentation any recommendations stay hypotheses – well informed but unvalidated guesses.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com