Exact(12)
They are more variable than most viral antigens known to bind endothelial receptors, but unusually conserved compared to other members of the extremely diverse PfEMP1 antigen family.
We use these values to assess unusually conserved regions.
Most of the unusually conserved introns are located in the 5' UTR regions.
However, it also indicates that the unusually conserved blocks we have identified among the four species must be under a considerable amount of selective pressure.
Adding the contributions from all of these comparisons would not be sufficient to bring the fraction of unusually conserved sequence up to that of yeast.
101, 103 Using adhesion domain classification, interstrain sequence comparisons have revealed a small number of tandem domain arrangements of 2 4 domains, called domain cassettes (DC), which are unusually conserved between parasite genotypes.
Similar(48)
FPSPD utilises environment-dependent substitution tables and evolutionary trace analysis to identify residues from a structurally-aligned homologous family of proteins that are unusually highly conserved.
These sequences were unusually well conserved in length, and contained many, almost invariable sequence motifs, which allowed high-quality alignments.
Genes that show unusually well conserved potential to bind Leu3 typically have binding sites that are themselves orthologous.
Our method searched human, mouse and rat transcripts in frames +1 and -1 for ORFs which are unusually well conserved at the amino acid level.
Mimivirus has unusually well conserved promoter-like AAAATTGA motifs in the upstream regions of half of its predicted genes in the genome [ 39].
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