Sentence examples for until receptor from inspiring English sources

Whether a common theme will emerge, i.e. that the kinases stabilise their cognate receptors until receptor activation, remains to be investigated.

This self-amplifying loop of increasing chemoattactrant signalling leading to more cell polarization goes on until receptor densensitization occurs.

Although ligand binding leads to receptor endocytosis, signaling can continue from endosomal compartments until receptors are sequestered from the cytoplasm [4] [7].

However, the site of MCH action remained obscure until its receptor was discovered in 1999 as a G protein-coupled receptor.

First, until recently, receptor blocking studies have not been performed in human subjects, and such studies are the 'gold standard' method of measuring the percentage of specific uptake of a PET radioligand.

For instance, in the absence of pERK-pFRS2 feedback loop, pERK levels increase according to our model simulations in response to FGFR activation and remain maximal until the receptor is internalized and degraded.

Signaling continues in endosomes [ 32] until the receptors are degraded in proteasomes and lysosomes.

Until recently, receptors for all peptides of the relaxin family were unknown.

The level of HER2 remains relatively unchanged until the receptors traffic to the lysosome at a later time point where the protein degradation occurs.

Until the receptors of teleost relaxin family genes are known and the physiological role of teleost rln understood, it will be difficult to assess this hypothesis.

It was an orphan receptor until 1999 when its natural ligand, ghrelin, was identified [1].