Sentence examples for until mutations from inspiring English sources

We found metastable coexistence of three strains in steady-state chemostats until mutations changed the relative fitness of competing strains.

An alternate explanation is that evolving strains drift under immune selective pressure until mutations have accumulated to the point where a novel genetic variant phenotype becomes established and evade from pre-established host immunity [35].

There was then a long hiatus until mutations in the TARDBP gene, which encodes the TDP-43 protein, were found in 2008 [ 16].

It turned out that this is a known disease with a known genetic basis, but with an atypical phenotypic presentation such that appropriate biochemical tests were not performed until mutations pointing to this syndrome were identified.

Targeted disruption of Foxl1 in mice is associated with hyperplasia of the gastric mucosa, abnormal crypt architecture and epithelial cell positioning in the small intestine and retarded growth [32,54]; its role in humans will be unclear until mutations or single gene deletions of FOXL1 are described in humans.

No more evolution will occur until mutation or migration creates variation at the locus again.

In practice, our population evolves under selection for folding into a given secondary structure until mutation-selection equilibrium is reached.

Generally, one mutation is not enough to cause cancer; the disease does not develop until other mutations occur.

Until such mutations are found, or someone finds an inherited mutation in the gene in persons with some form of hereditary cancer, it is "still up for grabs" whether p73 is a tumor suppressor, says cancer geneticist Bert Vogelstein of Johns Hopkins University School of Medicine.

This would promote a strictly asexual strategy until detrimental mutations in a clonal lineage result in reduced fitness.

Once proteo-microsatellites are formed mutation rates will increase with increasing repeat length, until new mutations or substitutions stabilize mutation rates and the microsatellite sequence [ 8, 9].