After their discovery by the German physician Paul Langerhans in 1868, their function remained obscure until it was realized that they are a vital part of the immunologic mechanism.
In the early days of chess, 2... e6 was played as a way of reaching a French Defense — that is, until it was realized that 3 d4 d5 was favorable for White.
In any case, the paradox was thought to be of minor importance until it was realized how detrimental it was to Gottlob Frege's theory of the foundations of mathematics.
Anyone can dream up great ideas, but an idea is nothing until it's realized, be it as a website, a physical product, an app or a user interface.
Any other biological consequence eluded us for several years until it was realized that within repetitive DNA the breakpoints within sister telomeres might be offset.
Exhaustion, severe anemia, nausea, and sterility were the norm after a course of treatment with the deep X-ray therapy favored by Martindale, until it was realized that the inhalation of the noxious gases produced by the apparatus was an important factor in the causation of X-ray sickness.
FASB doesnt have social media standards, but its broader guidelines hold that revenue should not be recognized until it is both realized (or realizable) and earned.
If the tax basis were held constant until the gain was realized, as it should be, then somebody sometime would pay income tax on the gain.
The true end of a rivalry is rarely realized until it is over.
In practice, applicants do often detail the experiments they plan to conduct, but many fail to realize until it is too late that experimental details are not enough!
