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To defend themselves against the deleterious effects of DSBs, eukaryotic organisms employ an intricate DNA damage response (DDR) pathway to detect DNA lesions, arrest the cell cycle until damaged DNA is repaired, and to induce cell death if the lesions are overwhelmed.
A key mechanism in this regulation is the DNA damage checkpoint, which operates throughout the cell cycle to prevent chromosome duplication or segregation until damaged DNA is repaired.
Although the product has yet to be field tested in an actual Midwest winter, the students say the bags are intended to be sturdy enough that they can stand up to salt and freezing conditions for weeks at a time, until damaged roads can be permanently fixed.
The building at its base, housing the Tower Ballroom, continued in use until damaged by fire in 1969.
As a consequence, cells are arrested at checkpoints until damaged DNA has been repaired.
Similar(55)
Mr. Spitzer said yesterday that officials of the association "were cooperative only until damaging information was uncovered".
It was not until damaging accusations about him from the bank's former head of regulatory risk Paul Moore were aired in parliament in February 2009 that he stepped down.
The longitudinal joints are continuously loaded until completely damaged.
Last year, a leak inside a wall was not discovered until water had damaged the building.
The giant bronze had stood in the lobby of 9 West 57th Street until it was damaged.
"You can't tell if it's damaged until you take it off the shelf," said a sister, Judith Lowry.
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CEO of Professional Science Editing for Scientists @ prosciediting.com