Sentence examples for untargeted manner from inspiring English sources

Metabolomics approaches for plants have now been around for little more than 10 years ([Fiehn et al. 2000]), and give us the capacity to study the biochemical composition of plant materials in an untargeted manner ([Hall 2006];[Hall 2011]).

While drugs can be used to achieve the inhibition of these enzymes in an untargeted manner, the precise mechanisms and the genetic cascades whereby these drugs induce biological changes are currently not completely understood and it seems to depend on cell micro-environment.

The aptly named XCMS program can thus be used to track the metabolism of isotopically labeled substrates in an untargeted manner revealing valuable insights into metabolic mechanisms.

This matching peak distribution between Cse4 and H2A confirmed that cenH3 nucleosomes can incorporate promiscuously at low levels in an untargeted manner.

P-element insertion occurs in an untargeted manner; thus, obtaining transgenes on a balancer requires one to create many independent insertions, and then to screen for those that happened to insert onto the balancer chromosome.

The histone-modifying enzymes affect histones either locally, through targeted recruitment by sequence-specific transcription factors (Rundlett et al, 1998), or globally throughout the genome in an untargeted manner affecting virtually all nucleosomes (Vogelauer et al, 2000).

A logical progression from the stable isotope targeted metabolomic technology is to follow the full conversion of the labeled isotopes in an untargeted unbiased manner, allowing observation of the metabolic fate of the metabolites.

In spite of its great promise, metabolomics has proven difficult to execute in an untargeted and generalizable manner.

Sample preparation was made in the same manner as for the untargeted analysis with some minor modification, as there was no second extraction performed.

Identifying features is the most time-demanding step of the untargeted metabolomic workflow and is generally performed in a targeted manner.

This is not surprising, since the data obtained through these untargeted experimental approaches was analyzed mainly in a hypothesis-driven, targeted manner.