These methods tend to rely heavily on prior knowledge about the disease, phenotype and/or genes, making them unsuitable systems for classifying novel and/or poorly characterized genes.
In embracing the Conservatives with evident relish, negotiating far more aggressively on positions in government than on promises about, above all, electoral reform, they showed themselves willing to shore up an unsuitable voting system (in parliament as well as on polling day).
However, it does not handle properly some major issues which make it unsuitable for systems where security is of concern.
This process requires the application of a considerable down-force to the sample in its polishing step, and hence could be unsuitable for systems containing mechanically weak dielectric layers under the Cu lines.
Adequate information systems are desperately needed with barriers operating at the level of users (poor training and support), the environment (poor infrastructure) and unsuitable software systems.
Furthermore, smaller NL sample size identified a reduced set of DMGs making this set of DMGs unsuitable for systems level analysis.
Or fiddling their economic figures for years to get into a completely unsuitable fixed currency system.
But the Games were a disaster, revealing Atlanta's inadequate transportation system, unsuitable climate and paucity of local leadership.
The lightweight structure makes the system unsuitable for buildings more than two floors high and going higher could be dangerous if done by amateurs.
Feedback channels introduce their own difficulties such as increased latency and buffering requirements, which makes the resultant system unsuitable for some applications.
The results show that the physics-based model is best able to capture results across all four representative data sets with an error less than 10%, but is 20x slower than the empirical model, and 134x slower than the semi-empirical model, making it unsuitable for powertrain system design and model-based algorithm development.
