Sentence examples for unsuitable loci from inspiring English sources

After removing unsuitable loci, primers were designed for 147 microsatellite regions using Primer3 within Geneious (Untergasser et al., 2012).

After removing unsuitable loci and including potentially heterozygous loci, a total of 1277 microsatellite regions remained, for which we attempted to design primers using Primer3 within Geneious (Rozen and Skaletsky, 2000).

This copy number state transformation before association testing made our association risk loci unsuitable to compare directly with other GWA studies.

As such, cluster patterns at these loci were either unsuitable for genotypic analysis due to mis-assignation of sub-clusters, or it was not possible to reliably determine the heterozygosity status of the parental genotypes, and thus the loci were not considered for further analyses.

We confirmed that Phsp60 induced stability problems leading to a significant proportion of the population having deletions in the promoter-reporter loci, making this promoter unsuitable for use in these conditions.

The human sequence was an unsuitable reference because the human OTOP1 locus diverged significantly from the orthologous regions in most other vertebrate genomes (see below).

FISH offers higher resolution (compared to SKY) and has the advantage of not requiring metaphase spreads, but is limited by the fact that it requires a prior hypotheses about the locus of interest, making it unsuitable for discovery based research.

Given that expression of our fluorescent protein-tagged 53BP1 derivative is correlated with higher foci counts, which may include numerous spuriously detected loci, we found this tool to be unsuitable for quantitative live-cell imaging.

Standard regression is unsuitable for this purpose, however, because even when the number of considered loci p is much fewer than the number of individuals n, LD creates multicollinearity that derails meaningful estimation of locus effects.

Repeat loci that did not yield a single PCR product were considered unsuitable.

These problems include families specifying a very broad range of miRNAs, which makes these families unsuitable for specific annotation and the Rfam miRNA families also come with a very high number of conflict loci without very strict filtering (see Methods section for details).