Despite harsh climate conditions, endemic diseases such as trypanosomiasis the African horse sickness and unsuitable terrain that limited the effectiveness of horses in many parts of Africa, horses were continuously imported and were, in some areas, a vital instrument of war.
This method is also unsuitable for polypharmacy, limiting the ecological validity of medication taking in RA where many patients are prescribed more than one DMARD, which in itself creates challenges to adherent behaviour.
However, these structures exhibited irregular morphology and unsuitable size, which would limit their in vivo application research.
Niche models showed that localities within population clusters each occupy areas of continuously high environmental suitability, but are separated from each other by large regions of completely unsuitable habitat that could limit dispersal.
The immediate recognition of other LkDT events sparsely distributed throughout the genome was limited by unsuitable PCR-based techniques.
Primary adrenal tumours such as functioning adenoma and carcinomas are normally treated with laparoscopic adrenalectomy, with percutaneous ablation limited to cases unsuitable for surgery [26].
The concentrations of ions (Ca+2, Mg+2, and Na+) have exceeded permissible limits, making the water unsuitable for domestic use.
Although lumped parameter models are conceptually simple and require limited data, they are unsuitable for characterising the internal dynamics of a hydrogeological system and/or under conditions where large scale anthropogenic stresses occur within a groundwater basin.
A previous study found that, despite expressing willingness to be involved in the delivery of unsupervised therapy, family viewed work commitments, lack of confidence and unsuitable treatment times as factors that would limit their participation [ 20].
It also indicated that methods with different selectivity, of which some are possibly unsuitable, could pass the existing system suitability limits.
