Moreover, these nanometer-sized metal oxides are not target-selective and are unsuitable for samples with complicated matrices.
For example, the EP-SM kit performs the centrifugation at 1,000 2,000 g in some cases, which may be fair for soils (the density is much higher than activated sludge), but unsuitable for sludge samples, and could cause loss of sample.
In addition, this technique may be unsuitable for CFA samples containing a high carbonaceous fraction and a low concentration of V because leaching V may not be efficient.
Ultrasound microbial cell disrupters operating at around 20 kHz are often physically large and, due to significant heating, can be unsuitable for small sample volumes where biochemical integrity of the extracted product is required.
Automatic techniques have been developed to segment cell nuclei from tissue sections or whole Drosophila brains in 2D and 3D images [12] [15], but they require intensive computation, making them unsuitable for large sample sizes.
Finally, the invasive nature of the biopsy makes it unsuitable for serial hepatic sampling.
Studying the time course of early effects originating after SCI is a complex task because in vivo animal experiments are usually unsuitable for repeated neuropathological sampling, and isolated spinal cord preparations survive in vitro for up to 24 h only.
Basanta-Sanchez et al. (2016) demonstrated a highly sensitive, accurate, quantitative UPLC-MS/MS nucleosides analysis method; however, this method applies to cellular RNA modifications and is thus unsuitable for human biological samples, such as blood and urine, due to its narrow calibration range.
Batches of some buffycoat extracts on filter paper (for DNA) stored in the freezer were soaked with water due to a freezer failure rendering some samples unsuitable for further analysis; the batch of samples of level 6 in Kerr Seringe was particularly affected (Table 2).
SRI-1/2/3 and SRII-1/2/3 were unsuitable for use with environmental samples because positive samples were not detected.
