Additionally, the patient population studied is skewed because all patients involved were those who had failed medical management and required surgical intervention, representing only the most severe forms of CRS, making it unsuitable for assessment of clinical measures.
Special attention is given to strength evaluation as the nonregular geometry of interlocking blocks makes standard methods of assessment unsuitable.
This readout could distinguish between involved and uninvolved skin, highlighting the compromised barrier function of psoriatic skin and corroborating the kinetic data, but demonstrated a high degree of noise in day to day readings across the time course which would make it unsuitable for longitudinal assessment of response to therapy in a clinical trial.
Forty-six patients were unsuitable for VF assessment because of moderate or severe learning disability and 11 patients had VFs that were thought to be unreliable.
A third group included cDNAs that did not produce gel-detectable PCR amplicons for any sample tested, and therefore, were unsuitable for quantitative assessment.
Therefore, the EFSA expert panel came to the conclusion that this casts doubt on the robustness of the observations and makes this study unsuitable for risk assessment (EFSA, 2006).
(100) A single ecological study linking the presence of high Cr VI) concentrations in drinking water to elevated mortality from stomach cancers did not include a dose-dependence analysis, 88) making it unsuitable for risk assessment.
The studies examining BPA in maternal and fetal blood samples also have a number of drawbacks that renders them unsuitable for an assessment of population exposures (Lee et al., 2008; Padmanabhan et al., 2008; Schönfelder et al., 2002b; Vandenberg et al., 2010a, 2010b): The extent of medical intervention during delivery is not reported.
Conconi et al. [ 26] proposed that a change in slope of the relationship between heart rate (HR) and exercise intensity (ATConconi) be used as a marker of AT, although this remains controversial and several authors concluded that most haemodynamic variables, including HR, are unsuitable for indirect assessment of the AT [ 27].
The authors of the latter study asserted that multiple choice questions may be unsuitable for formative assessments, because the "lures" or distractors create "false knowledge" [ 26].
