A total of 6944 women were not approached as they were either ineligible, missed in clinic, in another study, had a non-viable pregnancy, or were considered unsuitable to approach, e.g. having had a recent fetal loss.
In the presented PF tracking algorithm, likelihood evaluation can be computationally expensive, thus rendering this approach unsuitable for real-time systems.
However, generally, the nature of the entire physical and chemical processes which govern the observed phenomenon, are either unknown or too complex to be described by an analytical model, thereby rendering the physical model approach unsuitable.
The inability to modulate TEVp activity with rapamycin rendered this approach unsuitable.
These shortcomings make the approach unsuitable for routine use.
Thus, making this approach unsuitable for ChIP-seq, but provides a basis for a working scale ChIP reaction for limited cell amounts.
Even if the expertise and hardware capability for applying them were made available to local health departments, many time series are unsuitable for this approach.
Theoretically, though, it was possible that there were other, more subtle, differences in outcomes between these groups, which could have made this approach unsuitable.
This de-contextualisation of activation makes it impossible to address cross-talk or signal specificity, and makes the classical Boolean approach unsuitable for modelling of interactions between pathways in large complex networks.
Scientists have traditionally applied algorithms developed for ChIP-seq, without an input DNA control, to detect enriched DHSs although peculiarities of DNase-seq data render this approach unsuitable without adjustment of default settings at minimal [ 128].
With the anaerobic culture technique, the discrepancy between salivary recovery and subgingival presence has been significant, which makes this approach unsuitable for use in the microbial diagnosis of periodontitis patients [ 15].
