Unsuccessful modifications support discovery of limits to design changes, illuminate how designs work, and inform the generation of new design variations.
Richardson became a local symbol of the foreclosure crisis when her bank tried to seize her home despite months of unsuccessful loan modification attempts.
Zambian national guidelines, consistent with the Eighth Joint National Committee criteria, state that after unsuccessful lifestyle modification, antihypertensive treatment should start with one agent (hydrochlorothiazide-amiloride or a calcium channel blocker), with increasing doses or combinations if BP remains elevated [ 29, 30].
MnP from P. chrysosporium has been the target of most recombinant studies, which however suffer from unsuccessful posttranslational protein modification and the need for exogenous heme in high concentrations (Jiang et al.2008a).2008a
These results show that coupling success is highly dependent on the heterocycle, and in unsuccessful cases heterocycle modifications can be made to make the asymmetric Suzuki-Miyaura viable.
'Urinary marking is common in cats - it could be because he's being beaten up by other cats or another cat is coming in through the cat-flap.' If training and behaviour modification are unsuccessful, about one in 10 animal patients will be given antidepressants.
melting patterns have been unsuccessful, since the two modifications exhibit very similar melting temperatures.
If lifestyle modifications are unsuccessful, statins, drugs that act primarily by inhibiting cholesterol synthesis and also possibly by stabilizing the atherosclerotic plaque, are often prescribed to reduce the chances of a thrombotic event.
28 Pharmacological options are considered if lifestyle modifications prove unsuccessful.
With this phage attempts to close gaps between five contigs were unsuccessful probably due to substances or modifications inhibiting Taq and Φ29 polymerases and DNA restriction [ 22].
