While attempts to crystallize the ASV in complex with the D168A variant were unsuccessful, the interactions of the inhibitor are expected to be significantly disrupted as the Asp168A Arg155 ionic interaction will not exist.
During the interaction, the unsuccessful dialog data were also observed, which resulted from imperfect ASR results.
In other words, this account predicted a memory (successful, unsuccessful)×orientation (internal, external) interaction during encoding.
Attempts to identify regions of the IGF1R kinase important for maintaining the inactive state by either mutagenesis or inspection of kinase crystal lattices for a repeated interaction proved unsuccessful, however.
We discovered that micro-conflicts were followed by a relative reduction in uncertainty in successful design teams, whereas uncertainty rose after micro-conflicts in unsuccessful design teams, suggesting that interactions between conflict and uncertainty may be a differentiating factor for design team success.
However, many of the introductions seem to have been unsuccessful, possibly due to biotic interactions [47], [50].
Attempts to isolate sufficient soluble recombinant AtPEX7 for binding interaction studies were unsuccessful (data not shown) thus preventing application of the experimental approach presented above to determine the effect of PEX14N on the PEX7 PTS2 interaction.
This has important implications since the search for genetic associations with behavioural disorders would have been unsuccessful in these examples if interaction with the environmental pathogen had not been taken into account.
As stated by Hollnagel: 'The idea of a sociotechnical system is that the conditions for successful organizational performance – and conversely also for unsuccessful performance – are created by the interaction between social and technical factors' (2009, 19).
