The relatively short elimination half-life of lightly chlorinated PCBs could therefore lead to unstable tissue concentrations, and variable exposures could then easily affect the calculated partition coefficients.
The meniscus was then propped to ensure that all loose and weak fragments and unstable meniscus tissue had been successfully resected, preserving as much of the meniscus tissue as possible.
If the knee is still unstable, soft tissue procedures should be performed 6 8 months after correction of the malalignment.
The patient should be evaluated 6 8 months later, and if the knee is still unstable, soft tissue reconstruction should be performed.
This heterogeneity likely stems, at least partly, from the greater genotypic diversity of genomically unstable tumor tissue which has been exposed to the stresses of treatment.
The marsupial XCI is paternally imprinted (Cooper et al. 1971; Sharman 1971) and appears to be incomplete, unstable and tissue specific (reviewed in Deakin et al. 2009).
However, it has been reported that I3C is unstable in tissue culture medium and under acidic conditions, and is partially converted to the very stable compound, DIM (Bradfield and Bjeldanes, 1987; Ge et al, 1999; Staub et al, 2002).
This suggests that zβ1 variant C may be developmentally regulated, expressed in other tissues, unstable, or is the result of an infrequent alternative splicing event.
Interestingly PIN1 GFP S1,2,3E protein could not be detected at the apex as opposed to a nonmutated PIN1 GFP version, suggesting that apical localization renders PIN1 unstable in this tissue.
Of note, the conventionally used reference gene GAPDH proved to be quite unstable in our tissue samples, further underscoring the need for reference gene evaluation.
