For sufficiently low interfacial energies, the dislocation cores are unstable against the substitution by the pipes of the liquid phase (wetted core dislocation).
He explored international economics in his thesis ("Unstable velocity, volatile exchange rates and currency substitution: the demand for money in a multi-currency world").
We mapped this phosphorylation replacing each serine or threonine in this region with alanine by site-directed mutagenesis, except for Ser244 and Ser248, where the alanine substitutions were unstable in Escherichia coli and serine was replaced with glutamate instead.
Energy intensity and fuel substitution has mixed and unstable effect on the reduction of emission.
We can hypothesize that the T198A/G substitution results in an unstable conformation of the C-terminal tail of p27, which is then more rapidly recognized and degraded via the unfolded protein degradation system.
Here, electrophysiological characterization revealed that channels with a Pro inserted in this position behaved in a similar manner to Pro substitution at position 113: unstable in the open state, displaying extremely short open dwell times.
The prominent molecular feature of those with mutagenic effects (trichloro-, 1,1-dichloro-, and monochloroethylene) is unsymmetric chlorine substitution which renders the epoxides unstable, whereas symmetric substitution confers relative stability and nonmutagenic property.
The short branches in the center are unstable with respect to the choice of the substitution matrix used to construct the tree.
Substitution with four and five histidines (positions 3 7) generated unstable vault particles which appeared to separate into halves after assembly.
Furthermore, it shows that short-lived processes, that is, unstable gene expression, have weaker influence on the average substitution rate asymmetries than conserved processes.
