Indeed, the RcsB-DNA complex was reported to be unstable, and the role of RcsA proposed to stabilize this interaction [20], [29].
We provide the first direct evidence that truncating mutations in RAB23 are unstable, suggesting a role for NMD in pathogenesis, and describe the first homozygous mutations in RAB23 that encode single amino acid changes.
In contrast, action outcome mappings change unpredictably in unstable, uncertain environments; roles in organizations operating in such environments are necessarily emergent and open-ended.
We postulated that the gene duplication that generated these two types of subunits caused a likely evolutionarily unstable overlap of roles.
The risk of nuclear war is at its highest level since the early nineteen-eighties, with impulsive, unstable leaders elevating the role of nuclear weapons in their strategies and playing nuclear chicken in Northeast Asia.
Until we view this social calamity in its entirety — by also acknowledging the central role of unstable relations among the sexes and within poor families, by placing a far higher priority on moral and social reform within troubled black communities, and by greatly expanding social services for infants and children — it will persist.
In summary, the present study highlights the significant role of unstable housing in increasing premature mortality in PWID.
In the latter part of the paper, vascular pathogenesis theory based on the role of unstable OPP and autonomic dysregulation of the vessels will be highlighted.
However, in our study, the osteophytes were also found in the groove model, in which the joint does not become unstable arguing against their role in joint stabilization.
It is likely that the functional role of unstable proteins is regulated by their continual synthesis and degradation, while longer-lived proteins are regulated by modifications such as phosphorylation and acetylation.
