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As it has been described that Th1/17 (co-producing IL-17 and IFN- γ) cells may be generated by the plastic Th17 cell type, we generated clones from single sorted cells, and, we selected pure clones that stably maintained their phenotype over time (Supplementary Figure S1C), excluding all unstable profiles discriminating effectively between Th subsets.
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An unstable profile is believed to be a common feature among stress-induced proteins [ 39].
Furthermore, our results indicate that the Gm Hsp20s can be classified as unstable proteins, since 76.5% of aminoacid sequence showed an unstable profile (when instability index threshold were considered [ 38]) (see Additional file 2: Table S4).
(ii) To test that low PIPn values were due to unstable profile affiliations related to an insufficient number of taxa, we randomly removed half and three quarter of the species in each clade of the large mitochondrial dataset and recomputed PIPn.
Regions of unstable density profiles are shown to develop and persist in the field-scale experiment, which we attribute to regions of low hydraulic conductivity.
Chemical constituents of interest may move from the FFT into the lake water via two key processes: (1) advective-diffusive mass transport with upward pore water flow caused by settling of the FFT; and (2) mixing created by wind events or unstable density profiles through the lake water and upper portion of the FFT.
So they suggested that SBI of these locations could contribute to the autonomic dysfunction and also could be an explanation for the unstable BP profiles.
After sunrise, heating of the surface gradually erodes the stable atmosphere from below until the unstable daytime profile is reestablished.
This shaping stimulates the formation of defects in the graphitic lattice, which preferentially emit electrons, thereby enhancing the emission, however; this results in a temporally unstable emission profile.
A second group was found to have a more unstable CNA profile and focal amplifications of the ERBB2 genomic region.
It remains to be determined if non-invasive intermediate-lineage neoplasms can progress to invasive carcinoma and if small carcinomas arising de novo actually show the unstable CNA profile.
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