Sentence examples for unstable efficacy from inspiring English sources

But the efficacy of most herbal medications is influenced by many factors which may lead to unstable efficacy in clinical practice.

The resulting products may therefore be immunogenic, unstable and show reduced efficacy.

Unless we consider a so-called pro-drug, which requires metabolic activation for achieving efficacy, an otherwise unstable compound usually undergoes attrition during the drug development.

Development of a protein-based drug delivery system has major impact on the efficacy and bioavailability of unstable and water insoluble drugs.

Moreover, systemic administration of RNAs encounters several obstacles that reduce their therapeutic efficacy: they are highly unstable intravascularly, with a short half-life due to their susceptibility to serum nucleases and rapid renal clearance.

Numerical simulation of an unknown unstable system is presented to show the efficacy of the proposed approach.

Patients with a history of leukaemia or any other condition that might interfere with evaluations of treatment efficacy, such as epilepsy or unstable hypothyroidism, were excluded.

Unfortunately, BH4 is very unstable and, when orally administered, has limited efficacy likely due to oxidation during absorption (Cunnington et al., 2012).

However, the vehicle used for retinol delivery would play a crucial role in eliciting its efficacy, as retinol is extremely unstable and easily gets degraded to biologically inactive forms on exposure to light and air.

A previous study comparing psychoeducational training with waiting list also showed efficacy in symptoms such as impulsivity or unstable relationships but no improvement in psychosocial functioning [ 43].

This study was to assess the efficacy of the cervical cage in management of unstable Hangman's fracture combined with intervertebral disc injury.