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These parallels lead us to propose that there is a functional basis for the association of the tumour suppressor genes WWOX and FHIT with the most unstable common chromosomal fragile sites in humans.
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Another example is an ancient Tibetan proverb that goes, "When the emperor's position is unstable, the common people are also restless".
Half of the known miRNAs are located inside or close to fragile sites which are genomically unstable and common breakpoints associated with cancer.
Both stable (translocations, deletions and insertions) and the less common, unstable (dicentrics and fragments) chromosomal aberrations spontaneously accumulate with age.
Hospitalization for acute coronary syndromes (ACS), which includes both acute myocardial infarction (AMI) and unstable angina, is common and costly.
LTB4 and LXA4 are closely related metabolites of arachidonic acid and can be synthesised from a common unstable intermediate [ 3].
Acute coronary syndromes (ACS) are a set of presentations of coronary artery disease (CAD) and have in common unstable atherosclerotic coronary plaque.
High dropout rates and unstable attendance are common in the treatment of patients with PDs, and high attrition from follow-up evaluations may be a challenge in longitudinal studies of this patient group.
Other features of SNP environment such as location within a short dinucleotide repeat or nearby indel are sometimes more difficult to evaluate, as these regions are known to be genomically unstable, and represent common sites of true SNP formation (Pearson et al. 2005; Tian et al. 2008; Lopez Castel et al. 2010).
The hematopoietic differentiation process permits to follow the dynamic of a system when moving from a common unstable progenitor state to different stable attractors correspondent to the distinct cell types, each characterized by a clearly distinguished profile in the multidimensional transcript profile space.
But when combined with plentiful moisture and unstable air--common ingredients in the Pacific in the winter--conditions become perfect for more severe weather, he says.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com