Sentence examples for unstable classes from inspiring English sources
We measured the performance of the classifiers using ROC curves and found that the PETs performed better than the LOTs in situations where the number of instances of the stable and unstable classes were relatively balanced, but the LOTs did better where unstable examples were relatively rare compared to stable, perhaps due to the LOTs' ability to focus on individual examples.
Tables 2 and 3 show that in both stable and unstable classes there was an over-representation of the very low level disorder "hot loops: 0-20%" class.
This data was employed in all of the statistical analyses and the proteins in the stable and unstable classes were used for training and testing the models.
When evaluating the performance of our models on this data subset we trained using the full data set (i.e. the proteins in our stable and unstable classes), but tested only using these overlapping subsets.
We tested the ability of a strawman SVM trained on sequence data (we refer to this model as "SVM"), a BN integrating the aforementioned features (Tables 2 and 3) excluding sequence features (we refer to this model as "BN"), and a complete model (henceforth "BN+SVM"; Figure 2), to classify proteins into stable and unstable classes.
Although theoretically recognized for several decades as a common intermediate in many organic reactions, carbocations were unobservable because they were a short-lived, unstable class of compound.
14% of proteins fell into the unstable class, and 13% were assigned to the stable class.
This is supported by an under-representation of glycosylation modifications in the unstable class.
This resulted in 29% of proteins being assigned to an unstable class, and 26% to a stable class (Table 5).
We found that signaling proteins were highly over-represented in the P1 unstable class (Fisher's exact test, P = 3.08e-29).
Approximately 20% of the proteins fell into the unstable class, another 20% into the stable class, and the final 60% fell into the non-assigned class.
